一种:
What will he do with family next week?
可以用be going to 试试。
What is he going to do with family next week?
但回答会是:He is going to go fishing with family next week.
What will he do with family next week?
He will go fishing with family next week.
他下周要和家人做什么呢?
他下周要和家人钓鱼。
What will he do with his family next week?