一般疑问句： Is this your pencil case?
否定回答：No,it isn't.
is that your pencil case?
no, it isn't
一般疑问句，只需要把Be动词提前： (当主语为I/we/my/our时，提问要变成you/your)
Is this your pencil case?
No, It isn't.
Is that my pencil case?
No,that isn't.
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